Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
DNA Polymerase Kappa Research Products: Novus Biologicals
DNA polymerase η promotes nonhomologous end joining upon etoposide exposure dependent on the scaffolding protein Kap1 - Journal of Biological Chemistry
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity | HTML
A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ | PLOS ONE
DNA polymerase κ: Friend or foe? | Science Signaling
IJMS | Free Full-Text | Detours to Replication: Functions of Specialized DNA Polymerases during Oncogene-induced Replication Stress | HTML
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
Frontiers | DNA Damage Tolerance Pathways in Human Cells: A Potential Therapeutic Target
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms | ACS Chemical Biology
Translesion synthesis DNA polymerase η exhibits a specific RNA extension activity and a transcription-associated function | Scientific Reports
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms
Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance | Science Signaling
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
Science Signaling - The DNA polymerase Pol-kappa endows tumor cells with resistance to the BRAF inhibitor vemurafenib without increasing mutagenesis, according to new research from the White lab. https://fcld.ly/5jaum2s Credit: K. Temprine
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics